MDS Pharma Services provides pharmacokinetic analysis of parent drugs and metabolites using a variety of techniques, including noncompartmental, compartmental and population analysis. We also have significant experience in evaluating pharmacodynamic biomarkers related to efficacy and safety. The pharmacokinetics staff actively participates in study design, data analysis, interpretation, and reporting to ensure that study objectives are met. Our employees are familiar with many pharmacokinetic software packages available, including:

• PhAST (proprietary noncompartmental PK software)
• WinNonlin
• Kinetica
• Adapt-II
• NONMEM
• IT2S
• WinBugs

Early Clinical Research

Phase I-IIa

Bioequivalence Studies

PK/PD

Study Design and Protocol Development

Data Management

Statistical Analysis

PK/PD Analysis

Medical Writing and Reporting

Modeling and Simulation

Consultation